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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

Rat Caspase 3, CASP3 ELISA Kit

(1 Bausatz/-sätze = 495,00 €)

ab 495,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: E1648Ra


Beschreibung

Overview:

Target Protein: Caspase 3, CASP3

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -


Sensitivity: 0.02ng/ml

Detection range: 0.05-10ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Rat


Storage: 2 - 8°C

Assay Time: 1:30 h


Detailed Information:

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress.


CASP3 Information:

UniProt Accession: P55213

Synonyms: Apopain;CASP 3;CASP3;CASP-3;Caspase-3;Caspase-3 subunit p12;Caspase-3 subunit p17;CPP-32;Cysteine protease CPP32;IRP;LICE;Protein Yama;SCA-1;SREBP cleavage activity 1


References:



Supplier: BT-Labs