Rat Interleukin 1 Beta, IL-1B ELISA Kit

Overview:

Target Protein: Rat Interleukin 1beta (IL1B)

Size: 48T, 96T

Assay Type: Sandwich

One-Step: -

Sensitivity: 0.08ng/ml

Detection range: 0.2-60ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Rat

Storage: 2 - 8°C

Assay Time: 1:30 h

Detailed Information:

IL-1β is a member of the interleukin 1 family of cytokines. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

IL1B Information:

UniProt Accession: Q63264

Synonyms: IFN beta inducing factor;IL 1;IL 1 beta;IL1;IL-1;IL1 BETA;IL-1 beta;IL1B;IL-1B;il1b-A;IL1F2;Interleukin 1 beta;Interleukin 1 beta precursor;interleukin 1, beta;Interleukin-1 beta;OAF;Osteoclast activating factor;OTTHUMP00000162031

References:

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Supplier: BT-Labs