• 0941 948228
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  • 0941 948228
  • Sichere Bezahlung
  • Schneller Versand
  • Hohe Qualität
  • info@davids-bio.com

RGS14 Polyclonal Antibody

ab 295,00 €

zzgl. MwSt. zzgl. Versand

Artikelnummer: BT-AP07802


Beschreibung

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml


Detailed Information:

RGS14 encodes a member of the regulator of G-protein signaling family. Regulator of G-protein signaling 14 contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.


Antibody Production Information:

The antiserum was produced against synthesized peptide derived from human RGS14. AA range:125-174


Target:

Target: RGS14

Synonyms: RGS14; Regulator of G-protein signaling 14; RGS14


Supplier: BT-Labs