Beschreibung
Overview:
Clonality: Polyclonal
Host: Rabbit
Reactivity:Human, Mouse, Rat
Applications: WB, ELISA
Storage: -20°C for one year
Concentration: 1 mg/ml
Detailed Information:
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Antibody Production Information:
Synthesized peptide derived from human VE-Cadherin Polyclonal
Target:
Target: Cadherin-5
Synonyms: Cadherin-5 ;7B4 antigen;Vascular endothelial cadherin;VE-cadherin;CD antigen CD144; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD antigen CD144
Supplier: BT-Labs