Vinculin(Phospho Tyr821) Polyclonal Antibody

Overview:

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC-p, IF, ICC, ELISA

Storage: -20°C for one year

Concentration: 1 mg/ml

Detailed Information:

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Antibody Production Information:

The antiserum was produced against synthesized peptide derived from human Vinculin around the phosphorylation site of Tyr821. AA range:786-835

Target:

Target: Vinculin

Synonyms: Vinculin; VCL; Vinculin; Metavinculin

Supplier: BT-Labs